Talk:Rage/@comment-146.198.179.85-20170407190652/@comment-27029853-20170407191407

You can only reroll a die once per attack. If you roll 4 dice and 2 of them are hits, then you can only reroll the other two dice once, even if you have multiple effects that grant rerolls.

Because of this, the Target Lock and Rage don't synergize very well. If you're using Rage though, it's reasonably likely you'll be stressed next turn, in which case saving the target lock for that attack is probably best.